There are many neighborhoods in Holyoke. There were formed at different times and for different reasons.
Churchill
| tours of Churchill | tours of Churchill | tours of Churchill | charity |
| Chestnut Street tour | Sacred Heart Church and area | Second Congregational Church of Holyoke | Boys and Girls Clubs of Greater Holyoke |
| Sons of Zion Cemetery (Chicopee) | Notre Dame Cemetery (South Hadley) | Wistariahurst | |
| Holyoke on the National Register | Holyoke Heritage Trail | ||
| Perpetual Help Church and area | Holyoke Library Commons |
Downtown
Elmwood
| tour of Elmwood | sponsor | |
| Blessed Sacrament Church and neighborhood | Greensfield Coin and Stamp of Holyoke (permanently closed) | |
| Calvary Cemetery | ||
| Elmwood Cemetery | ||
| Elmwood Park |
Flats
Highlands and Highland Park
| tours of the Highlands and of Highland Park | ||
| Four Churches in the Highlands | The Parish and the Hill (by Mary Doyle Curran) tour | |
| Fairfield Avenue | Kennedy Park | |
| Jones Point Park | Rohan Park | |
| Wyckoff Park |
Homestead Avenue and Jarvis Avenue Neighborhood
| tours of Homestead Avenue and Jarvis Avenue neighborhood | ||
| Ashley Reservoir | ||
| Community and Anniversary Fields | ||
Ingleside and Whiting Farms
| tours of Ingleside and tours of Whiting Farms | sponsor | |
| Mont Marie Cemetery | Homewood Suites by Hilton | |
| Calvary Cemetery of the Sisters of Providence | Brad Matthew Jewelers | |
| Brightside Neighborhood | ||
Oakdale
| tours of Oakdale | ||
| Forestdale Cemetery | ||
| Saint Jerome Cemetery | ||
Smith’s Ferry and Rock Valley
| tours of Smith’s Ferry and Rock Valley | ||
| Whiting Street Reservoir | Rock Valley Cemetery | |
| Smith’s Ferry Cemetery | ||
South Holyoke and Springdale
| tours of South Holyoke and tours of Springdale | charity | |
| Holyoke on the National Register | Providence Ministries | |
| Third Level Canal | ||
| Precious Blood Church | ||
| Precious Blood Cemetery | ||
| Springdale Park |